Erectile dysfunction disease means that you cannot get or maintain a suitable penile erection. There are some of the many causes, the most common being due to contraction of the tubes, which takes blood to the penile region. Tadalafil 40 mg in Tadalista 40 mg helps in working by inhibiting the action of a compound in the form, known as phosphodiesterase type 5. This can assist in relaxing blood veins and enhancing the flow of blood to the penile region, which helps in following sexual stimulation. This medicine helps man to achieve and sustain maintain a stiffer erection in the presence of sexual stimulation.