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Anabolic steroids
Anabolic steroids are drugs that imitate the action of natural male sex hormone - testosterone and dihydrotestosterone. Anabolic steroid drugs increase the speed of proteins activity inside skin cells, which causes said muscles hypertrophy. That’s why they are used in bodybuilding widely... The actions of anabolic steroid drugs can be conventionally divided into two parts: anabolic activity and androgenic activity. The expressed word “anabolic”, mentioning to anabolism, comes from the Ancient greek “anabole” (ἀναβολή) - “that which is certainly placed up, pile”, and the expression androgenic from the Ancient greek language “andros” (ἀνδρός) - “of a gentleman” + “genes” (γενής), "delivered".
Background of anabolic steroids
The usage of gonadal steroids pre-dates their identification and isolation. Medical make use of testicle get commenced in the later 19tl century. In 1931 Adolf Butenandt filtered 15 milligrams of the guy hormone androstenone from tens of hundreds of litres of urine. This steroid was eventually synthesized in 1934 by Leopold Ruzicka.
In the 1930s, it was already known that the testes contain an extra highly effective androgen than androstenone. Three teams of researchers, financed by fighting pharmaceutic corporations in the Netherlands, Belgium, and Swiss, ran to separate it. This hormone was first discovered by Karoly Gyula David, Age. Dingemanse, T. Freud and Ernst Laqueur in a Might 1935 newspaper "On Crystalline Guy Hormone from Testicles (Testosterone)." They called the hormone testo-sterone, from the stems of sterol and testicle, and the suffix of ketone.
The chemical synthesis of testosterone was achieved in July that year by Butenandt and G. Hanisch. Just a week afterwards, the third group, A and Ruzicka. Wettstein, declared a patent request. Ruzicka and Butenandt had been presented the 1939 Nobel Winning prize in Biochemistry and biology for their job.
